Key result
Familial hyperlipoproteinemia was documented in 31% of children from families where one parent had a myocardial infarction before age 50.
Why the study?
What is the frequency of familial hyperlipoproteinemia in children of parents with premature myocardial infarction?
Population
223 children from 70 families where one parent had a myocardial infarction before age 50
Design
Cross-sectional
Authors
Loading...
Supports family history-guided lipid evaluation in children; leaves open prospective validation before practice change.
Observational (n=223)
What is the frequency of familial hyperlipoproteinemia in children of parents with premature myocardial infarction?
There is a high frequency (31%) of familial hyperlipoproteinemia in children of parents with premature myocardial infarction, emphasizing the need for early pediatric screening based on family history.
Charles J. Glueck (1974) conducted an observational in Family history of premature myocardial infarction (n=223). Family history of premature myocardial infarction was evaluated on Frequency of familial hyperlipoproteinemia in children. Familial hyperlipoproteinemia was documented in 31% of children from families where one parent had a myocardial infarction before age 50.