Key result
Quad-site pacing using an additional temporary left ventricular lead increased dP/dt(max), whereas multisite pacing using the Quartet lead alone did not improve acute hemodynamic response.
Why the study?
Does quad-site pacing using an additional temporary LV lead improve acute hemodynamic response compared to multisite pacing using a quadripolar LV lead alone in patients undergoing CRT?
Does quad-site pacing using an additional temporary LV lead improve acute hemodynamic response compared to multisite pacing using a quadripolar LV lead alone in patients undergoing CRT?
Quad-site pacing utilizing an additional temporary LV lead, but not multisite pacing with a single quadripolar lead alone, improves acute hemodynamic response during CRT.
Answers are grounded in this paper and cite their sources.
Temporary quad-site pacing may enhance acute CRT hemodynamics; leaves open whether quadripolar leads alone enable effective multisite pacing.
Pacing the left ventricle (LV) from multiple sites simultaneously may result in a better response to cardiac resynchronization therapy (CRT). We sought to assess whether multisite pacing using a quadripolar LV lead improves acute hemodynamic response (AHR) to CRT. We paced four ventricular sites simultaneously using two vectors of a Quartet lead, a right ventricular apical lead, and an additional LV lead temporarily placed in an anterior branch of the coronary sinus. Multisite pacing using the Quartet lead alone did not improve the AHR but "quad-site" pacing using an additional temporary LV lead did increase dP/dt(max).
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Shetty et al. (2011) studied Cardiac resynchronization therapy (CRT) indication. Quad-site pacing using an additional temporary LV lead vs. Multisite pacing using the Quartet lead alone was evaluated on Acute hemodynamic response (AHR) measured by dP/dt(max). Quad-site pacing using an additional temporary left ventricular lead increased dP/dt(max), whereas multisite pacing using the Quartet lead alone did not improve acute hemodynamic response.
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