Key result
Achieving blood pressure control after 3 months of treatment was associated with a greater decrease in plasma BNP levels compared to poor control (median change -14.5 vs -1.3 pg/ml, P<0.001).
Why the study?
Does antihypertensive treatment and subsequent blood pressure control reduce plasma BNP levels in patients with newly diagnosed essential hypertension?
Population
186 individuals with newly diagnosed essential hypertension without target organ damage, mean age 48.7 +/…
Comparison
Antihypertensive treatment initiated with… vs Patients with poor BP control.
Design
Cohort
Follow-up
3 months
Authors
Loading...
May support BNP as a treatment-response marker in hypertension; hypothesis-generating and requires prospective validation before clinical use.
Cohort (n=186)
Does antihypertensive treatment and subsequent blood pressure control reduce plasma BNP levels in patients with newly diagnosed essential hypertension?
Absolute Event Rate: -14.5% vs -1.3%
p-value: p=<0.001
Plasma BNP levels correlate with systolic blood pressure and decrease significantly upon achieving blood pressure control, suggesting its potential as a biomarker for effective hypertension management.
Andreadis et al. (2009) conducted a cohort in newly diagnosed essential hypertension (n=186). Achieved blood pressure control vs. Poor blood pressure control was evaluated on Change in plasma BNP levels (p=<0.001). Achieving blood pressure control after 3 months of treatment was associated with a greater decrease in plasma BNP levels compared to poor control (median change -14.5 vs -1.3 pg/ml, P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: