The Multi-Pixel Photon Counter (MPPC) is a Geiger-mode avalanche photo-diode (APD) developed by Hamamatsu Corp. We propose that it could be a suitable photo-sensor for next-generation time-of-flight PET detectors due to its high photon detection efficiency. We concentrate on the measurement of coincidence timing performance of various MPPCs in conjunction with LYSO crystal scintillators. With 3 mm times 3 mm devices of 50 mum sub-pixels coupled to 3 mm times 3 mm times 10 mm LYSO crystals, we have demonstrated a strong dependence of timing performance on over-voltage and temperature, and analyzed how changes in photon detection efficiency and dark counts would explain the measurements. The best coincidence timing resolution we have achieved between two identical LYSO/MPPC detectors was 240 ps in FWHM. This was worse than the timing resolution of 220 ps obtained with a Hamamatsu H6533 fast PMT, and contradicted the expected improvement from higher photon detection efficiency. The contradiction could be explained by the slow rise-time of MPPC pulse shape, transit time spread, dark counts and electronic noise from the large capacitance of the MPPC. In particular, the slow rise-time of the MPPC pulse suggests the need for a very low trigger threshold on the timing circuit. Since this makes the detector system more sensitive to noise, this poses additional challenges for ganging multiple devices together into a commercially viable time-of-flight PET block detector. We will discuss this work in detail including other challenge imposed by MPPC characteristics.
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Kim et al. (2009) studied this question.
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