Key result
Albuminuria shows no link to insulin resistance despite ~5-fold higher obesity in the top quartile.
Why the study?
Is albuminuria associated with insulin resistance and metabolic syndrome in never-treated, non-diabetic hypertensive men?
Cross-Sectional (n=271)
Is albuminuria associated with insulin resistance and metabolic syndrome in never-treated, non-diabetic hypertensive men?
In never-treated, non-diabetic hypertensive men, albuminuria is independent of insulin resistance and metabolic syndrome, but is associated with higher blood pressure and obesity.
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Supports decoupling albuminuria from insulin resistance in non-diabetic hypertension; leaves open BP- and obesity-driven pathways for prospective validation.
Pedrinelli et al. (2003) conducted a cross-sectional in essential hypertension (n=271). Albuminuria and microalbuminuria vs. Lower urine albumin levels was evaluated on Insulin resistance (HOMA) and related metabolic abnormalities. Albuminuria was independent of insulin resistance and metabolic syndrome traits, though obesity was fivefold more frequent in the top versus bottom urine albumin quartile.
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