Why the study?
Is microalbuminuria in essential hypertension associated with impaired insulin-mediated glucose uptake?
Population
20 accurately matched hypertensive patients with (n=10) or without (n=10) microalbuminuria.
Comparison
Oral glucose ingestion and 2-hour euglycemic… vs Hypertensive patients without microalbuminuria.
Design
Case-control
Authors
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Microalbuminuria may mark insulin resistance in hypertension; hypothesis-generating, needs prospective validation before clinical use.
Is microalbuminuria in essential hypertension associated with impaired insulin-mediated glucose uptake?
Microalbuminuria in essential hypertension is associated with a selective impairment in peripheral insulin-mediated glucose uptake and an enhanced insulin secretory response to glucose.
Bianchi et al. (1995) studied this question.
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