Key result
Apixaban stabilizes chronic DIC and resolves bleeding and thrombosis symptoms in two patients.
Why the study?
While heparins are beneficial in disseminated intravascular coagulation, the safety and efficacy of direct oral anticoagulants have not yet been sufficiently addressed.
Does oral apixaban improve clinical symptoms and laboratory parameters in patients with chronic disseminated intravascular coagulation?
Case Report (n=2)
Does oral apixaban improve clinical symptoms and laboratory parameters in patients with chronic disseminated intravascular coagulation?
Oral apixaban may be a safe and effective treatment option for managing chronic disseminated intravascular coagulation caused by vascular abnormalities.
No takes yet. Share an insight, caveat, or question.
Apixaban may stabilize chronic DIC symptoms; case reports leave open need for controlled trials before clinical adoption.
Janjetovic et al. (2018) conducted a case report in Chronic disseminated intravascular coagulation (DIC) (n=2). Apixaban was evaluated on Improvement in DIC parameters and clinical symptoms. Apixaban administration stabilized chronic DIC in two patients, leading to improved DIC parameters and clinical resolution of bleeding and thrombosis symptoms.
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