What is the clinical evidence from this study?

Study design: Observational. Population: Ischaemic congestive heart failure. Intervention: Raised NT-proBNP concentrations. Primary outcome: Ventricular tachyarrhythmia.

August 14, 2006HeartOpen Access

Raised B-type natriuretic peptide predicts implantable cardioverter-defibrillator therapy in patients with ischaemic cardiomyopathy

Q: What are the key findings of this study?

The study evaluated whether raised NT-proBNP concentrations predict ventricular tachyarrhythmia in patients with ischaemic CHF, but results were not provided in the truncated abstract.

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Key result

Study assesses whether raised NT-proBNP predicts ventricular tachyarrhythmia in ischemic CHF but lacks reported results.

Why the study?

Do raised NT-proBNP concentrations predict ventricular tachyarrhythmia in patients with ischaemic CHF and an ICD device?

Population

Patients with ischaemic congestive heart failure undergoing implantable cardioverter-defibrillator…

Design

Cohort

Follow-up

1 year (first postoperative year)

Authors

RKR KlingenbergUniversity of Zurich

Discussion

Member takes

Implication

NT-proBNP should not yet guide VT risk assessment in ischaemic CHF with ICD; leaves open its predictive value.

Study Design

Type

Observational

Structured PICO

Do raised NT-proBNP concentrations predict ventricular tachyarrhythmia in patients with ischaemic CHF and an ICD device?

Population

Patients with ischaemic congestive heart failure and LVEF <= 30% undergoing ICD implantation, followed for one year.

Exposure

Raised N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations measured at ICD implantation.

Outcome

Ventricular tachyarrhythmia (as a surrogate marker of sudden cardiac death) assessed via ICD interrogation during the first postoperative year.surrogate

Cite This Study

R Klingenberg (2006) conducted an observational in Ischaemic congestive heart failure. Raised NT-proBNP concentrations was evaluated on Ventricular tachyarrhythmia. The study evaluated whether raised NT-proBNP concentrations predict ventricular tachyarrhythmia in patients with ischaemic CHF, but results were not provided in the truncated abstract.

synapsesocial.com/papers/6aa346fa4af3e7a0b24c12e2 https://doi.org/10.1136/hrt.2005.076117

Topics

Heart failure HFrEF treatment Cardiac device therapy Women and heart disease

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Raised B-type natriuretic peptide predicts implantable cardioverter-defibrillator therapy in patients with ischaemic cardiomyopathy

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Topics

Raised B-type natriuretic peptide predicts implantable cardioverter-defibrillator therapy in patients with ischaemic cardiomyopathy

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Topics

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