Key result
Acute pneumonia and pulmonary embolism in rabbits reduce pulmonary and bronchial blood flows in parallel.
Why the study?
How does acute lobar pneumonia and pulmonary embolism affect blood flow in the pulmonary and bronchial arteries in rabbits?
How does acute lobar pneumonia and pulmonary embolism affect blood flow in the pulmonary and bronchial arteries in rabbits?
Effect estimate: r=0.65
Acute pneumonia and pulmonary embolism both significantly reduce pulmonary and bronchial artery blood flow in a parallel manner in a rabbit model.
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Does not inform human management of pneumonia or embolism; leaves open whether parallel bronchial-pulmonary flow reductions occur clinically.
Björk et al. (1977) studied Acute lobar pneumonia and pulmonary embolism. Induced acute lobar pneumonia and pulmonary embolism vs. Normal lung was evaluated on Blood flow in the pulmonary artery and bronchial arteries (r=0.65). Induced acute pneumonia and pulmonary embolism in rabbits reduced pulmonary and bronchial artery blood flows compared to normal lungs, with reductions paralleling each other (r=0.65).
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