Key result
MOLLI agrees with TI scout for myocardial T1 measurement after adjusting for acquisition time.
Why the study?
Does myocardial T1 measurement using MOLLI provide comparable values to TI scout in patients without delayed enhancement?
Population
390 participants from the Multi-Ethnic Study of Atherosclerosis without finding of delayed enhancement
Comparison
Myocardial T1 measurement using MOdified… vs Myocardial T1 measurement using TI scout sequence
Design
Cross-sectional
Authors
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Supports MOLLI as time-adjusted alternative to TI scout; leaves open prospective validation before clinical adoption.
Observational (n=390)
Yes
Does myocardial T1 measurement using MOLLI provide comparable values to TI scout in patients without delayed enhancement?
Mean Difference: 2.7
Absolute Event Rate: 460.8% vs 463.6%
p-value: p=0.16
Myocardial T1 measurement using MOLLI is reproducible and comparable with TI scout when adjusted for acquisition time differences.
Liu et al. (2012) conducted an observational in Without finding of delayed enhancement (n=390). MOLLI (Modified Look-Locker Inversion-recovery) vs. TI scout was evaluated on Post-contrast myocardial T1 value (MD 2.7, p=0.16). Myocardial T1 measurement using MOLLI showed good agreement with TI scout after adjusting for acquisition time differences (mean difference 2.7 msec; p=0.16).
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