Key result
Insulin reverses increased forearm blood flow and prolonged reactive hyperaemia linked to juvenile diabetic ketosis.
Why the study?
Does insulin treatment reverse vascular abnormalities such as prolonged reactive hyperaemia in juvenile diabetics with ketosis?
Population
Juvenile diabetics with moderate ketosis and mild disturbances of blood acid-base balance, non-diabetics…
Comparison
Insulin treatment vs Pre-treatment baseline, non-diabetic controls…
Design
Other
Authors
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Insulin may normalize ketosis-linked forearm hyperemia in juvenile diabetes; leaves open whether these changes predict complications or warrant targeted therapy.
Observational
Does insulin treatment reverse vascular abnormalities such as prolonged reactive hyperaemia in juvenile diabetics with ketosis?
Diabetic ketosis is associated with reversible vascular abnormalities, specifically increased resting blood flow and prolonged reactive hyperaemia, which normalize following insulin administration.
Niels Juel Christensen (1970) conducted an observational in Diabetic ketosis. Diabetic ketosis vs. Non-diabetics and post-insulin treatment state was evaluated on Resting forearm blood flow and reactive hyperaemia. Diabetic ketosis in juvenile diabetics was associated with increased resting forearm blood flow and prolonged reactive hyperaemia, which reversed after insulin treatment.
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