Key result
Age is linked to increased fibrin and fibrinolytic activity.
Why the study?
How do fibrin content and fibrinolytic activity vary with age, sex, and history of cerebral vascular accidents?
Population
Three 'normal' groups and a fourth group of middle-aged people with previous cerebral vascular accident…
Design
Cross-sectional
Authors
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Associations with age and prior CVA should not yet guide clinical decisions; hypothesis-generating for longitudinal fibrin dynamics in cardiovascular risk.
Observational
How do fibrin content and fibrinolytic activity vary with age, sex, and history of cerebral vascular accidents?
Fibrin and fibrinolytic activity increase with age, and there may be an association between increased antifibrinolytic activity and prior cerebral vascular accidents.
Robert Hume (1961) conducted an observational in Cerebral vascular accident. Previous cerebral vascular accident and age vs. Normal individuals was evaluated on Fibrin content and fibrinolytic activity. Age was associated with increased fibrin and fibrinolytic activity, while previous cerebral vascular accident was associated with non-significantly higher fibrin and lower fibrinolytic activity.
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