Key result
Rapid intravenous inulin clearance correlates strongly with eGFR with a ~4.5 mL/min average difference.
Why the study?
Does rapid intravenous injection of an inulin fraction accurately measure glomerular filtration rate compared to standard GFR parameters in nephrology patients?
Population
27 patients admitted to the Nephrology ward, mean age 67.8 ± 12.9 years, 15 male / 12 female.
Design
Cross-sectional
Follow-up
24 hours
Authors
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Rapid intravenous injection of inulin provides a concise and accurate alternative to the conventional drip-infusion method for measuring glomerular filtration rate.
Observational (n=27)
No
Does rapid intravenous injection of an inulin fraction accurately measure glomerular filtration rate compared to standard GFR parameters in nephrology patients?
Effect estimate: r = 0.8286-0.8650
Rapid intravenous injection of inulin provides a concise and accurate alternative to the conventional drip-infusion method for measuring glomerular filtration rate.
Maeda et al. (2011) conducted an observational in Chronic Kidney Disease (n=27). Rapid intravenous injection of inulin (Inulead) vs. Estimated GFR (eGFR) and other GFR parameters was evaluated on Correlation between inulin clearance (Cin) by rapid injection and estimated GFR (eGFR) (r = 0.8286-0.8650). Inulin clearance measured by rapid intravenous injection of inulin correlated well with estimated GFR (r = 0.8286-0.8650), with an average difference of -4.4 to -4.5 mL/min.
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