Key result
Hyperbaric oxygenation prolongs survival in pigs with gradual coronary occlusion, permitting detectable myocardial infarctions.
Why the study?
Does hyperbaric oxygenation improve survival and affect myocardial infarction incidence in pigs with gradual coronary artery occlusion?
Population
24 young farm pigs with gradual occlusion of the left anterior descending coronary artery produced by…
Comparison
Hyperbaric oxygenation in a hyperbaric chamber… vs Handled in a similar manner outside the chamber…
Design
Preclinical
Follow-up
Maximum of 32 hours of treatment
Authors
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Hyperbaric oxygenation may extend survival in porcine gradual occlusion; leaves open human translation and clinical relevance.
Does hyperbaric oxygenation improve survival and affect myocardial infarction incidence in pigs with gradual coronary artery occlusion?
Prolonged hyperbaric oxygenation may lengthen survival during and after coronary occlusion in a pig model, allowing time for pathologically detectable myocardial infarctions to develop.
Peter et al. (1966) studied Coronary artery occlusion (n=24). Hyperbaric oxygenation vs. Air at normal atmospheric pressure was evaluated on Survival and incidence of myocardial infarction. Hyperbaric oxygenation prolonged survival in pigs with gradual coronary occlusion, permitting the development of pathologically detectable myocardial infarctions.
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