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July 16, 2015European Journal of Gastroenterology & Hepatology

Celiac disease is linked to higher pulse wave velocity indicating increased arterial stiffness versus healthy controls.

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Why the study?

Is celiac disease associated with increased arterial stiffness in patients without traditional cardiovascular risk factors?

Population

58 adult patients with celiac disease without cardiovascular risk factors, and age-matched and sex-matched…

Design

Case-control

Key result

Celiac disease was associated with higher 24-hour, day, and night pulse wave velocity values compared to healthy controls (P<0.05), indicating increased arterial stiffness.

Authors

HKHüseyin Anıl KorkmazMSMehmet SözenLKLevent Kebapçılar

Discussion

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Overview

May warrant vascular assessment in celiac patients without traditional risks; leaves open causal mechanisms and therapeutic implications.

Study Design

Type

Observational

Structured PICO

Is celiac disease associated with increased arterial stiffness in patients without traditional cardiovascular risk factors?

P
Population
Adult patients with celiac disease without cardiovascular risk factors compared to age- and sex-matched healthy controls.
C
Comparator
Age-matched and sex-matched healthy controls
O
Outcome
Arterial stiffness evaluated using pulse wave velocity (PWV)surrogate

Main Result

p-value: p=<0.05

Celiac disease is associated with increased arterial stiffness and inflammatory markers even in the absence of traditional cardiovascular risk factors.

Cite This Study

Korkmaz et al. (2015) conducted an observational in Celiac disease. Celiac disease vs. Healthy controls was evaluated on Arterial stiffness assessed by pulse wave velocity (PWV) (p=<0.05). Celiac disease was associated with higher 24-hour, day, and night pulse wave velocity values compared to healthy controls (P<0.05), indicating increased arterial stiffness.

synapsesocial.com/papers/6aa5fe9a86a9fcb249922d02https://doi.org/10.1097/meg.0000000000000437
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Also Consider

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