Key result
Complicated pregnancy history linked to ~72% higher rheumatic disease prevalence and worse systolic ventricular performance.
Why the study?
The study aimed to evaluate echocardiographic aspects in women with a history of preeclampsia or preeclampsia-related complications in previous pregnancies.
Does a history of complicated pregnancy (preeclampsia) worsen long-term echocardiographic parameters and increase cardiovascular risk factors in women?
Observational (n=545)
Does a history of complicated pregnancy (preeclampsia) worsen long-term echocardiographic parameters and increase cardiovascular risk factors in women?
Odds Ratio: 1.72 (95% CI 1.1688–2.5191)
Absolute Event Rate: 33% vs 22.3%
p-value: p=0.006
A history of preeclampsia or complicated pregnancy is associated with long-term subclinical structural and functional left ventricular modifications and increased cardiovascular risk factors.
May support rheumatic screening evaluation after complicated pregnancy; hypothesis-generating for ventricular effects, requiring prospective validation before practice change.
No takes yet. Share an insight, caveat, or question.
Nicolini et al. (2021) conducted an observational in History of preeclampsia or complicated pregnancy (n=545). History of complicated pregnancy (preeclampsia or related complications) vs. History of physiological pregnancy was evaluated on Prevalence of rheumatic diseases (OR 1.72, 95% CI 1.1688-2.5191, p=0.006). A history of complicated pregnancy was associated with a higher prevalence of rheumatic diseases (33% vs 22.3%; OR 1.72; P=0.006) and worse longitudinal systolic ventricular performance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: