Key result
Riboflavin deficiency in mice is linked to slightly greater resistance to Lansing strain poliomyelitis virus.
Population
Mice fed an adequate diet, save for various levels of riboflavin, injected with Lansing strain poliomyelitis…
Comparison
Various levels of riboflavin vs Adequate diet (normal riboflavin levels)
Design
Preclinical
Authors
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Does not support changing human riboflavin intake; hypothesis-generating for nutrition-virus interactions in models.
Riboflavin deficiency in mice may confer slight resistance to experimental infection with Lansing strain poliomyelitis virus.
Rasmussen et al. (1944) studied this question. Riboflavin deficiency in mice was associated with slightly greater resistance to Lansing strain poliomyelitis virus (n=234), with no consistent effect on susceptibility to Theiler's virus.
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