Why the study?
The study was conducted to comparatively analyze features of LV myocardial remodeling in pregnant women with chronic arterial hypertension and preeclampsia on the background of chronic arterial hypertension across different ethnic groups.
Population
547 pregnant women with hypertensive disorders from Dagestan and Sakha (Yakutia)
Comparison
CAH vs PE on the background of CAH across 2 ethnic cohorts
Design
Cohort study
Key result
Preeclampsia superimposed on chronic arterial hypertension in pregnant women was associated with a significantly higher frequency of concentric left ventricular hypertrophy by the third trimester compared to chronic arterial hypertension alone (42.6% vs 31.3%, p=0.03).
Authors
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May warrant closer monitoring in superimposed preeclampsia; leaves open whether concentric LVH predicts outcomes or guides therapy.
Observational (n=547)
Yes
Absolute Event Rate: 42.6% vs 31.3%
p-value: p=0.03
Ethnic and geographic factors influence the pattern of left ventricular remodeling in pregnant women with chronic arterial hypertension and preeclampsia, with inappropriate left ventricular mass serving as a potential predictor for preeclampsia.
Gasanova et al. (2022) conducted an observational in Chronic arterial hypertension and preeclampsia in pregnancy (n=547). Preeclampsia superimposed on chronic arterial hypertension vs. Chronic arterial hypertension alone was evaluated on Frequency of concentric left ventricular hypertrophy (cLVH) in the third trimester (p=0.03). Preeclampsia superimposed on chronic arterial hypertension in pregnant women was associated with a significantly higher frequency of concentric left ventricular hypertrophy by the third trimester compared to chronic arterial hypertension alone (42.6% vs 31.3%, p=0.03).
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