Key result
High impedance ventricular leads extend estimated generator longevity by ~13 months versus conventional leads.
Why the study?
The impact of high impedance ventricular leads on pacemaker generator longevity compared to conventional leads was evaluated in a prospective randomized trial.
Does a high impedance ventricular lead improve generator longevity compared to a conventional lead in patients requiring ventricular pacing?
Comparison
High impedance ventricular lead (CapSure Z) vs conventional ventricular lead (CapSure SP)
Design
Prospective randomized trial
Follow-up
12 months
Authors
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High-impedance leads may reduce generator replacements in paced patients; extends RCT evidence for lead selection in device longevity.
RCT (n=89)
randomized
Does a high impedance ventricular lead improve generator longevity compared to a conventional lead in patients requiring ventricular pacing?
Absolute Event Rate: 94.5% vs 81.1%
The use of high impedance ventricular leads significantly reduces energy consumption and extends estimated pacemaker generator longevity by over a year compared to conventional leads.
Scherer et al. (2001) reported an RCT. High impedance ventricular lead (CapSure Z) vs. Conventional lead (CapSure SP) was evaluated on Estimated time to replacement (generator longevity). High impedance ventricular leads (CapSure Z) increased estimated mean generator longevity to 94.5 months compared to 81.1 months with conventional leads.
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