What is the clinical evidence from this study?

Study design: Other. Population: Carotid artery stenosis. Intervention: Varying degree of carotid artery stenosis. Primary outcome: Spatial and temporal variations of wall shear stress (WSS) and oscillatory shear index (OSI).

What does this research mean for the field?

High carotid artery stenosis leads to increased normalized wall shear stress in the internal carotid artery and decreased normalized wall shear stress in the common carotid artery. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 27, 2016Journal of Mechanics in Medicine and Biology

Wall Shear Stress and Oscillatory Shear Index Distribution in Carotid Artery With Varying Degree of Stenosis: A Hemodynamic Study

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Key result

High carotid stenosis models show higher ICA and lower CCA wall shear stress.

Population

3D models generated from multiple CT volumes of subjects in the carotid bifurcation zone with varying…

Design

Preclinical

Authors

PBPRASHANTH BASAVARAJANational Institute of Technology Karnataka AGAjay GuptaGeneral Cardiology LSLuca SabaCardiac Imaging

Discussion

Member takes

Implication

Hypothesis-generating in animal carotid stenosis models; leaves open whether spatial shear metrics improve human stenosis assessment.

Structured PICO

Population

3D models generated from multiple CT volumes of subjects in the carotid bifurcation zone with varying degrees of carotid artery stenosis

Exposure

Finite volume-based computational fluid dynamics (CFD) method to simulate hemodynamics in pulsatile flow conditions

Outcome

Spatial and temporal variations of wall shear stress (WSS) and oscillatory shear index (OSI)surrogate

Computational fluid dynamics modeling suggests that spatial average values of oscillatory shear and limiting streamlines may be more accurate than maximum values for assessing carotid stenosis severity and atherogenesis risk.

Cite This Study

BASAVARAJA et al. (2016) studied Carotid artery stenosis. Varying degree of carotid artery stenosis was evaluated on Spatial and temporal variations of wall shear stress (WSS) and oscillatory shear index (OSI). High carotid artery stenosis models demonstrated larger normalized wall shear stress in the internal carotid artery and smaller values in the common carotid artery.

synapsesocial.com/papers/6aa888f8e6e04d1cc73c7653 https://doi.org/10.1142/s0219519417500373

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July 27, 2016Journal of Mechanics in Medicine and Biology

Wall Shear Stress and Oscillatory Shear Index Distribution in Carotid Artery With Varying Degree of Stenosis: A Hemodynamic Study

View Full Paper

Ask AI

Bookmark

Key result

High carotid stenosis models show higher ICA and lower CCA wall shear stress.

Population

3D models generated from multiple CT volumes of subjects in the carotid bifurcation zone with varying…

Design

Preclinical

Authors

PBPRASHANTH BASAVARAJANational Institute of Technology Karnataka AGAjay GuptaGeneral Cardiology LSLuca SabaCardiac Imaging

Discussion

Member takes

Implication

Hypothesis-generating in animal carotid stenosis models; leaves open whether spatial shear metrics improve human stenosis assessment.

Structured PICO

Population

3D models generated from multiple CT volumes of subjects in the carotid bifurcation zone with varying degrees of carotid artery stenosis

Exposure

Finite volume-based computational fluid dynamics (CFD) method to simulate hemodynamics in pulsatile flow conditions

Outcome

Spatial and temporal variations of wall shear stress (WSS) and oscillatory shear index (OSI)surrogate

Cite This Study

synapsesocial.com/papers/6aa888f8e6e04d1cc73c7653 https://doi.org/10.1142/s0219519417500373

Also Consider

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