Key result
Essential hypertension linked to ~26% lower peak exercise endocardial GLS, indicating impaired LV contractile reserve.
Why the study?
The study evaluated the diagnostic utility of treadmill exercise stress echocardiography combined with LV layer-specific strain for assessing subclinical myocardial and reserve function in hypertensive patients.
Does treadmill exercise stress echocardiography combined with layer-specific strain detect subclinical myocardial and reserve dysfunction in patients with essential hypertension?
Observational (n=106)
Does treadmill exercise stress echocardiography combined with layer-specific strain detect subclinical myocardial and reserve dysfunction in patients with essential hypertension?
Absolute Event Rate: 22.8% vs 30.8%
Treadmill exercise stress echocardiography combined with layer-specific strain is a sensitive method for detecting impaired left ventricular contractile reserve in essential hypertension.
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May aid early detection of subclinical LV impairment in hypertension; hypothesis-generating and should not yet change practice.
Wang et al. (2022) conducted an observational in Essential hypertension (n=106). Essential hypertension vs. Controls was evaluated on Global longitudinal endocardium strain (GLSendo) at peak exercise. Essential hypertension was associated with reduced global longitudinal endocardium strain at peak exercise compared to controls (22.8% vs 30.8%), indicating impaired left ventricular contractile reserve.