Key result
Highest Geriatric Nutritional Risk Index quartile linked to ~64% lower odds of heart failure.
Why the study?
The study was conducted to investigate the correlation between the geriatric nutritional risk index (GNRI) and the occurrence of heart failure in older adults.
Does a higher Geriatric Nutritional Risk Index (GNRI) associate with a reduced prevalence of heart failure in adults aged 60 and older?
Population
16,021 participants aged 60 and older from NHANES
Comparison
Participants categorized into quartiles based on GNRI scores
Design
Cross-sectional study
Authors
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Supports GNRI screening in older adults for HF risk stratification; leaves open whether nutritional interventions alter incidence.
Cross-Sectional (n=16,021)
Yes
Does a higher Geriatric Nutritional Risk Index (GNRI) associate with a reduced prevalence of heart failure in adults aged 60 and older?
Odds Ratio: 0.36 (95% CI 0.23–0.56)
p-value: p=<0.001
Higher Geriatric Nutritional Risk Index (GNRI) scores are independently associated with a lower prevalence of heart failure in older adults, suggesting nutritional status is an important indicator of heart failure risk.
Gao et al. (2025) conducted a cross-sectional in Heart Failure (n=16,021). Geriatric Nutritional Risk Index (GNRI) vs. Lowest GNRI quartile (Q1) was evaluated on Prevalence of heart failure (OR 0.36, 95% CI 0.23-0.56, p=<0.001). Higher Geriatric Nutritional Risk Index scores were significantly associated with a lower prevalence of heart failure, with individuals in the highest quartile having 64% lower odds compared to the lowest quartile (OR 0.36).
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