Key result
ACE gene polymorphism links to serum ACE activity but not blood pressure in Japanese children.
Cross-Sectional (n=122)
The insertion/deletion polymorphism of the ACE gene strongly influences serum ACE levels as early as childhood in the Japanese population, without affecting blood pressure.
No takes yet. Share an insight, caveat, or question.
Genotype should not inform pediatric BP assessment; extends ACE polymorphism–activity link to Japanese children but leaves hypertension implications open.
Yamamoto et al. (1997) reported a cross-sectional. ACE gene insertion/deletion polymorphism was evaluated on Serum ACE activity and blood pressure. ACE gene insertion/deletion polymorphism was significantly associated with serum ACE activity in Japanese children aged 10-15 years, with no association found for blood pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: