Key result
Antilipolytic agents are linked to elevated plasma GH in sheep, indicating FFA's role in GH homeostasis.
Why the study?
The influence of plasma free fatty acid levels on growth hormone secretion in ruminants was investigated to understand GH homeostasis.
Population
Sheep
Comparison
Antilipolytic agents vs infusion of acetate, propionate, triglyceride and heparin
Design
Experimental study using various antilipolytic agents
Authors
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Should not change practice; leaves open FFA-GH feedback for validation beyond sheep models.
Hertelendy et al. (1973) studied this question. Antilipolytic agents (3,5-dimethyl pyrazole, nicotinic acid, salicylate, and insulin) was evaluated on Plasma growth hormone (GH) levels. Inhibition of fat mobilization by antilipolytic agents in sheep was associated with highly significant elevations of plasma growth hormone levels, indicating FFA's role in GH homeostasis.
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