Key result
High GRACE, EF ≤40%, and no prior ACEI/ARB linked to higher in-hospital mortality in ACS >80.
Why the study?
ACS has become more frequent in the elderly population due to increased life expectancy, but predictors of in-hospital mortality in patients over 80 years with ACS are not well defined.
Observational (n=171)
No
Odds Ratio: 1.074 (95% CI 1.039–1.11)
p-value: p=<0.001
In very elderly patients (over 80 years) presenting with ACS, a high GRACE risk score, low ejection fraction, and lack of ACEI/ARB use are significant predictors of in-hospital mortality.
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May guide risk stratification in octogenarian ACS; leaves open whether ACEI/ARB use improves outcomes.
Samet Yılmaz (2018) conducted an observational in Acute coronary syndrome (n=171). High GRACE risk score vs. Lower GRACE risk score was evaluated on In-hospital mortality (OR 1.074, 95% CI 1.039-1.110, p=<0.001). A high GRACE risk score (OR 1.074), ejection fraction ≤40% (OR 8.113), and no prior use of ACEI/ARB were significantly associated with in-hospital mortality in ACS patients over 80 years old.
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