Key result
Angiographic coronary thrombus presence shows no association with 3-year MACE rates compared to its absence.
Why the study?
The distribution of thrombus-containing lesions in an all-comer PCI population and their long-term prognostic implications remain unclear and disputed.
Does the presence of angiographic coronary thrombus increase major adverse cardiac events in patients treated with percutaneous coronary intervention?
Cohort (n=4,450)
Yes
Does the presence of angiographic coronary thrombus increase major adverse cardiac events in patients treated with percutaneous coronary intervention?
Absolute Event Rate: 25.3% vs 25.4%
p-value: p=0.683
The presence of angiographic coronary thrombus in an all-comer PCI population does not appear to adversely affect long-term clinical outcomes at 3 years.
No takes yet. Share an insight, caveat, or question.
Angiographic TCLs confer no excess 3-year risk after PCI; leaves open whether quantitative thrombus burden refines prognostication.
Campos et al. (2015) conducted a cohort in Stable angina, unstable angina, or acute coronary syndrome treated with percutaneous coronary intervention (n=4,450). Angiographic thrombus-containing lesions (TCL) vs. Absence of angiographic TCL was evaluated on Major adverse cardiac events (composite of death, myocardial infarction, and repeat revascularization) (p=0.683). Angiographic coronary thrombus presence did not significantly affect the 3-year rate of major adverse cardiac events compared to its absence (25.3% vs 25.4%; P=0.683).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: