Key result
Dialysis-induced hypotension is linked to bradycardiac collapse in ~54% of cases and decreased peripheral resistance.
Why the study?
The haemodynamic changes during dialysis-induced hypotension in uraemic patients have not been fully characterized using continuous beat-to-beat monitoring.
Population
52 uraemic patients undergoing haemodialysis
Comparison
Haemodynamic parameters during hypotension vs baseline during haemodialysis
Design
Observational study using electrical bioimpedance cardiography
Follow-up
During the haemodialysis session
Authors
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Parasympathetic overactivity may contribute to dialysis hypotension; leaves open whether Bezold-Jarisch reflex modulation improves intradialytic stability.
Observational (n=52)
Dialysis-induced hypotension is frequently associated with a paradoxical bradycardiac response, suggesting parasympathetic overactivity potentially related to the Bezold-Jarisch reflex.
Santoro et al. (1990) conducted an observational in Uraemia (n=52). Haemodialysis-induced hypotension was evaluated on Haemodynamic changes during acute hypotension. Dialysis-induced hypotension was associated with decreased systolic arterial pressure (-39.3%) and total peripheral resistance (-36.3%), with bradycardiac collapse observed in 54% of cases.
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