Key result
Carvedilol is linked to improved cerebral perfusion and cerebrovascular reserve in hypertension and T2DM.
Why the study?
The impact of hypotensive therapy on cerebral perfusion in patients with arterial hypertension associated with type 2 diabetes mellitus was not well characterized.
Does carvedilol therapy improve cerebral perfusion and cerebrovascular reserve in patients with arterial hypertension and type 2 diabetes mellitus?
Observational
Does carvedilol therapy improve cerebral perfusion and cerebrovascular reserve in patients with arterial hypertension and type 2 diabetes mellitus?
Carvedilol therapy for 6 months improves cerebral perfusion and cerebrovascular reserve in patients with hypertension and type 2 diabetes.
Answers are grounded in this paper and cite their sources.
May support carvedilol for cerebral perfusion in hypertension with T2DM; hypothesis-generating, needs RCTs before practice change.
The article is devoted to the estimation of the impact of hypotensive therapy on the state of cerebral perfusion in patients with AH, associated with type 2 DM using99mTc-HMPAO brain SPECT. It has been shown that the signs of the brain hypoperfusion and reduced cerebrovascular reserve are observed in patients with AH in combination with type 2 DM even when focal neurological symptoms are absent. Using99mTc-HMPAO brain SPECT it has been found that carvedilol therapy of about 6 months has a positive effect on the cerebral perfusion and cerebrovascular reserve status in these patients.
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Ефимова et al. (2015) conducted an observational in Arterial hypertension associated with type 2 diabetes mellitus. Carvedilol was evaluated on Cerebral perfusion and cerebrovascular reserve status. Carvedilol therapy for about 6 months had a positive effect on cerebral perfusion and cerebrovascular reserve status in patients with arterial hypertension and type 2 diabetes mellitus.
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