Key result
HFpEF shows no difference in long-term mortality versus HFrEF in hospitalized patients.
Authors
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No change to risk stratification by EF warranted in acute HF; leaves open whether phenotype-specific therapies improve outcomes.
Observational (n=1,217)
Yes
Hazard Ratio: 0.93 (95% CI 0.664–1.303)
Absolute Event Rate: 22.7% vs 17.8%
p-value: p=0.675
Tsuchihashi‐Makaya et al. (2009) conducted an observational in Heart Failure (n=1,217). Heart failure with preserved ejection fraction vs. Heart failure with reduced ejection fraction was evaluated on All-cause mortality (Adjusted HR 0.930, 95% CI 0.664-1.303, p=0.675). In hospitalized patients with heart failure, there was no significant difference in long-term adjusted all-cause mortality between those with preserved versus reduced ejection fraction (adjusted HR 0.930, p=0.675).
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