Key result
Maximal C-IMT and plasma homocysteine independently predict CV mortality, with C-IMT linked to ~271% higher risk.
Why the study?
The utility of carotid intima-media thickness and plasma homocysteine levels in predicting future cardiovascular events and death remains debated.
Do increased carotid intima-media thickness and plasma homocysteine levels predict cardiovascular and all-cause mortality in a geriatric cohort?
Cohort (n=1,391)
Do increased carotid intima-media thickness and plasma homocysteine levels predict cardiovascular and all-cause mortality in a geriatric cohort?
Hazard Ratio: 3.709 (95% CI 1.202–11.446)
Increased carotid intima-media thickness and plasma homocysteine levels are independent predictors of cardiovascular and all-cause mortality in a geriatric population.
No takes yet. Share an insight, caveat, or question.
C-IMT and homocysteine may refine mortality risk stratification in older adults; leaves open whether they improve clinical prediction models beyond standard factors.
Jung et al. (2013) reported a cohort. Carotid intima-media thickness and plasma homocysteine levels was evaluated on Cardiovascular mortality (HR 3.709, 95% CI 1.202-11.446). Average maximal carotid intima-media thickness (HR 3.709; 95% CI 1.202-11.446) and plasma homocysteine levels independently predicted cardiovascular mortality.
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