Key result
Linezolid initiated shortly after paroxetine discontinuation is linked to serotonin syndrome.
Population
1 patient who initiated linezolid therapy shortly after discontinuation of therapy with a selective…
Design
Case_report
Authors
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May warrant vigilance for serotonin syndrome when starting linezolid soon after SSRI cessation; leaves open interaction incidence and optimal washout timing.
Highlights the risk of serotonin syndrome when initiating linezolid shortly after discontinuing an SSRI like paroxetine.
Wigen et al. (2002) studied this question. Linezolid therapy initiated shortly after discontinuation of the selective serotonin reuptake inhibitor paroxetine resulted in a case of serotonin syndrome.
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