Key result
Female sex in TAVR was associated with lower rates of acute kidney injury (P=0.05) and pacemaker insertion (P<0.00001), but higher rates of mortality, stroke, bleeding, and vascular complications.
Why the study?
Are there sex-related differences in postoperative outcomes between males and females undergoing transcatheter aortic valve replacement?
Population
Patients undergoing transcatheter aortic valve replacement from 28 retrospective and prospective studies
Comparison
Female sex vs Male sex
Design
Meta-analysis
Follow-up
in-hospital / postoperative
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May support sex-specific TAVR risk counseling; leaves open mechanisms and mitigation strategies for female-specific complications.
Meta-Analysis
Are there sex-related differences in postoperative outcomes between males and females undergoing transcatheter aortic valve replacement?
In patients undergoing TAVR, females have lower rates of AKI and pacemaker insertion but higher rates of in-hospital mortality, stroke, bleeding, and vascular complications compared to males.
A 2022 study conducted a meta-analysis in Aortic stenosis. Female sex vs. Male sex was evaluated on Postoperative outcomes including acute kidney injury, pacemaker insertion, in-hospital mortality, stroke, bleeding, and vascular complications. Female sex in TAVR was associated with lower rates of acute kidney injury (P=0.05) and pacemaker insertion (P<0.00001), but higher rates of mortality, stroke, bleeding, and vascular complications.
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