Key result
Targeted rotor ablation eliminates refractory VF at 6-month follow-up off antiarrhythmics in case report.
Why the study?
Critical ventricular fibrillation-sustaining substrate in ischemic cardiomyopathy may be located predominantly in the left ventricle and is not necessarily associated with LAVA and fractionation, requiring targeted ablation strategies.
Case Report
Rotor mapping and targeted ablation of VF-sustaining substrate can be safely performed via a single arterial access site and successfully eliminate VF in patients with ischemic cardiomyopathy.
May support rotor ablation for refractory VF in ischemic cardiomyopathy; leaves open generalizability beyond case reports.
Key Teaching Points•Targeted ablation of rotational functional substrate can successfully eliminate ventricular fibrillation at 6-month follow-up off of antiarrhythmic medications.•In patients with ischemic cardiomyopathy, critical ventricular fibrillation (VF)-sustaining substrate may be located predominantly in the left ventricle and is not necessarily associated with local abnormal ventricular activities (LAVA) and fractionation.•Rotor mapping and ablation of VF-sustaining substrate may be safely performed with only a single arterial access site. •Targeted ablation of rotational functional substrate can successfully eliminate ventricular fibrillation at 6-month follow-up off of antiarrhythmic medications.•In patients with ischemic cardiomyopathy, critical ventricular fibrillation (VF)-sustaining substrate may be located predominantly in the left ventricle and is not necessarily associated with local abnormal ventricular activities (LAVA) and fractionation.•Rotor mapping and ablation of VF-sustaining substrate may be safely performed with only a single arterial access site.
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Ho et al. (2018) conducted a case report in Ventricular fibrillation in ischemic cardiomyopathy. Targeted ablation of rotational functional substrate via a single arterial access site was evaluated on Elimination of ventricular fibrillation. Targeted ablation of rotational functional substrate via a single arterial access site successfully eliminated ventricular fibrillation at 6-month follow-up off antiarrhythmic medications.
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