Key result
Family history of hypertension linked to ~8% higher carotid-femoral pulse wave velocity in healthy individuals.
Why the study?
A positive family history of hypertension is a risk factor for cardiovascular diseases, but its association with arterial stiffness in healthy subjects was investigated.
Does a positive family history of hypertension increase carotid-femoral pulse wave velocity in healthy subjects?
Population
255 healthy subjects (75 male, 180 female)
Comparison
With positive family history of hypertension vs without family history
Design
Cross-sectional study
Authors
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Higher CF-PWV may flag early vascular changes in familial hypertension; leaves open its value for risk stratification pending prospective data.
Cross-Sectional (n=255)
Does a positive family history of hypertension increase carotid-femoral pulse wave velocity in healthy subjects?
Absolute Event Rate: 7.9% vs 7.32%
p-value: p=<0.001
A positive family history of hypertension is associated with increased arterial stiffness in healthy individuals, suggesting early vascular changes prior to clinical disease.
Liu et al. (2015) conducted a cross-sectional in Healthy subjects (n=255). Positive family history of hypertension vs. No family history of hypertension was evaluated on Carotid-femoral pulse wave velocity (CF-PWV) (p=<0.001). Healthy subjects with a positive family history of hypertension had significantly higher carotid-femoral pulse wave velocity than those without such a history (7.90 vs 7.32 m/s; p<0.001).
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