Key result
Antigenic variation of the Foot and Mouth Disease Virus, driven by high mutation rates and continuous field circulation, significantly challenges vaccine efficacy and disease control efforts.
Design
Review
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Antigenic variation in FMD virus may hinder vaccine matching; leaves open need for ongoing field surveillance and strain updates.
Antigenic variation in Foot and Mouth Disease Virus, driven by high mutation rates and genetic recombination, poses a significant challenge to vaccine efficacy and causes severe economic losses in livestock.
Longjam et al. (2011) conducted a review in Foot and mouth disease. Antigenic variation of the Foot and Mouth Disease Virus, driven by high mutation rates and continuous field circulation, significantly challenges vaccine efficacy and disease control efforts.
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