Key result
Supportive therapy, high-dose lorazepam, 10 ECT sessions, and careful olanzapine titration achieved a return to baseline in a 33-year-old woman with catatonia after clozapine discontinuation.
Case Report (n=1)
ECT and careful reintroduction of atypical antipsychotics (olanzapine) can successfully treat catatonia following clozapine withdrawal when neuroleptic malignant syndrome cannot be ruled out.
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May support ECT plus olanzapine in clozapine-withdrawal catatonia when NMS uncertain; hypothesis-generating from single case.
Koch et al. (2013) conducted a case report in Catatonia (n=1). Supportive therapy, high dose lorazepam, ECT, and olanzapine was evaluated on Clinical improvement and return to baseline. Supportive therapy, high-dose lorazepam, 10 ECT sessions, and careful olanzapine titration achieved a return to baseline in a 33-year-old woman with catatonia after clozapine discontinuation.
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