Why the study?
Do calcium channel blockers reduce stroke recurrence and improve cognitive and blood pressure outcomes in stroke patients?
Population
1,067 stroke patients pooled from 13 randomized controlled trials
Comparison
Calcium channel blockers (CCB) vs Control group (not explicitly defined in abstract)
Design
Meta-analysis
Key result
Calcium channel blockers significantly reduced the recurrence rate of stroke (MD 0.41; 95% CI 0.24-0.70; P=0.0009) and improved cognitive function scores.
Authors
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CCBs reduce stroke recurrence and improve cognition in treated patients; reinforces their suitability in post-stroke care based on 13 RCTs.
Meta-Analysis (n=1,067)
Do calcium channel blockers reduce stroke recurrence and improve cognitive and blood pressure outcomes in stroke patients?
Mean Difference: 0.41 (95% CI 0.24–0.7)
p-value: p=0.0009
Calcium channel blockers effectively prevent stroke recurrence and improve cognitive recovery in stroke patients.
Feng et al. (2021) conducted a meta-analysis in Hypertensive stroke (n=1,067). Calcium channel blockers vs. Control was evaluated on Recurrence rate of stroke (MD 0.41, 95% CI 0.24-0.70, p=0.0009). Calcium channel blockers significantly reduced the recurrence rate of stroke (MD 0.41; 95% CI 0.24-0.70; P=0.0009) and improved cognitive function scores.