Key result
Rosa roxburghii fruit flavonoids reduced carrageenan-induced thrombosis, oxidative stress, and inflammation in mice by suppressing the NF-κB pathway and altering intestinal flora.
Why the study?
Does Rosa roxburghii fruit flavonoids extract prevent carrageenan-induced thrombosis in mice?
Population
Mice with carrageenan-induced thrombosis model
Design
Preclinical
Authors
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RF may attenuate thrombosis in mice; leaves open human efficacy and should not change practice.
Does Rosa roxburghii fruit flavonoids extract prevent carrageenan-induced thrombosis in mice?
Rosa roxburghii fruit flavonoids demonstrate antithrombotic, anti-inflammatory, and antioxidant effects in a mouse model of carrageenan-induced thrombosis.
Pu et al. (2023) studied Carrageenan-induced thrombosis. Rosa roxburghii fruit flavonoids (RF) was evaluated on Thrombosis (length of black tail and hemagglutination parameters). Rosa roxburghii fruit flavonoids reduced carrageenan-induced thrombosis, oxidative stress, and inflammation in mice by suppressing the NF-κB pathway and altering intestinal flora.