Key result
Intravenous corticosteroids resulted in rapid and complete recovery of ventricular function in 5 patients with acute heart failure related to multiple sclerosis relapses.
Why the study?
Acute heart failure related to multiple sclerosis relapses is rare and not well characterized, particularly its association with takotsubo cardiomyopathy.
Case Report (n=5)
Answers are grounded in this paper and cite their sources.
Acute heart failure presenting as takotsubo cardiomyopathy can be a rare manifestation of multiple sclerosis relapses, which responds well to intravenous corticosteroids.
We report 5 cases of acute heart failure (AHF) related to multiple sclerosis (MS) relapses. AHF was inaugural in 3 patients, always preceded or accompanied by signs of brainstem dysfunction; it was severe, requiring intensive care management. Echocardiography showed left ventricular hypokinesis. No other cause of AHF has been found. All patients showed a new medullary lesion on brain magnetic resonance imaging. All had rapid and complete recovery of ventricular function after intravenous corticosteroids. We concluded that the cases represent a takotsubo phenomenon. Physicians should be aware of rare cases of takotsubo cardiomyopathy in MS relapses. Ann Neurol 2017;81:754-758.
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Androdias et al. (2017) conducted a case report in Acute heart failure related to multiple sclerosis relapses (n=5). Intravenous corticosteroids was evaluated on Recovery of ventricular function. Intravenous corticosteroids resulted in rapid and complete recovery of ventricular function in 5 patients with acute heart failure related to multiple sclerosis relapses.
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