Key result
Avalus bioprosthesis yields ~88% 5-year survival with no structural valve deterioration after SAVR.
Why the study?
The safety, durability, and haemodynamic performance of a stented bovine pericardial valve for surgical aortic valve replacement require evaluation through 5 years of follow-up.
Does surgical aortic valve replacement with a stented bovine pericardial bioprosthesis provide safe, durable, and hemodynamically stable outcomes at 5 years?
Cohort (n=1,118)
Does surgical aortic valve replacement with a stented bovine pericardial bioprosthesis provide safe, durable, and hemodynamically stable outcomes at 5 years?
The Avalus stented bovine pericardial bioprosthesis demonstrates excellent 5-year safety, survival, and hemodynamic stability with no structural valve deterioration in patients undergoing surgical aortic valve replacement.
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Supports Avalus durability at 5 years in SAVR; leaves open need for randomized comparisons.
Klautz et al. (2022) conducted a cohort in Indication for surgical aortic valve replacement (n=1,118). Avalus stented bovine pericardial valve was evaluated on Overall survival (95% CI 85.9-90.0). Surgical aortic valve replacement with the Avalus valve demonstrated an 88.1% survival rate at 5 years (95% CI 85.9-90.0%), with no cases of structural valve deterioration.
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