Key result
Glucose loading reveals impaired glucose tolerance linked to FFA drops in ~67% of young MI patients.
Why the study?
The behavior of glucose tolerance and free fatty acid changes after glucose loading in myocardial infarction patients without diabetes was not well characterized.
Does glucose loading reveal impaired carbohydrate metabolism and altered free fatty acid behavior in young patients with myocardial infarction?
Comparison
Glucose tolerance and FFA changes vs normal subjects
Design
Observational study
Authors
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Acute glucose loading may flag metabolic stress in younger MI patients; leaves open its value for risk stratification or intervention.
Observational (n=43)
Does glucose loading reveal impaired carbohydrate metabolism and altered free fatty acid behavior in young patients with myocardial infarction?
Young patients with myocardial infarction frequently exhibit impaired glucose tolerance but normal adipose tissue insulin response, suggesting a differential effectiveness of insulin that may be linked to arteriosclerosis.
Cohen et al. (1965) conducted an observational in Myocardial infarction (n=43). Glucose loading vs. Normal subjects was evaluated on Glucose tolerance and free fatty acid decrease. Glucose loading in patients under 50 with myocardial infarction revealed impaired glucose tolerance in the majority, associated in two thirds of cases with a prompt decrease in free fatty acids.
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