Key result
High-grade chest wall sarcoma links to fatal eosinophilic endomyocardial disease in a rare case presentation.
Why the study?
Eosinophilic endomyocardial disease is usually of unknown cause but has been associated with malignant tumours, with limited prior reports linking it to chest wall sarcoma.
Case Report (n=1)
Supports consideration of occult malignancy in unexplained eosinophilic endomyocardial disease; extends known paraneoplastic associations but remains hypothesis-generating.
Eosinophilic endomyocardial disease is characterised by persisting blood eosinophilia and acute endocardial lesions which progress to endomyocardial fibrosis. In most cases the cause is unknown but it has been described in association with malignant tumours. A fatal case is presented of a 64 year old woman with this disease due to a high grade sarcoma of the chest wall, an association not previously reported.
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Thwaites et al. (1994) conducted a case report in Eosinophilic endomyocardial disease (n=1). High grade chest wall sarcoma was evaluated. A fatal case of eosinophilic endomyocardial disease was reported in a 64-year-old woman, uniquely associated with a high grade sarcoma of the chest wall.
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