Key result
Preoperative hypertension and prior MI are linked to postoperative changes in LVEF.
Why the study?
The impact of various pre-operative risk factors on outcomes following CABG in patients with CAD and different LVEF levels was not well characterized.
Cross-Sectional (n=54)
No
p-value: p=0.002
These associations may guide future risk models; Level 5 evidence leaves open prospective validation before clinical use.
Background: Coronary Artery Bypass Graft (CABG) is done in patient with Coronary Artery Disease (CAD) with Normal or decreased Left Ventricular Ejection Fraction (LVEF). Most of the patient with CAD presents with NYHA class II or III. Methods: It’s an analytical study of retrospectively collected data of all patients who underwent CABG for CAD. Data were collected over the period of about 30 months at Nobel Medical College and Teaching Hospital. Results: There were a total of 54 patients in our study. There was male 38 (72%) predominance. There were 49 (92.5%) cases having BMI <30 kg/m2. However only 2 (4%) had COAD, 23 (43%) had DM II, 9 (17%) had abnormal thyroid function, 6 (11%) were dyslipidemic and 1 (2 %) had a prior history of CVA. There were 23 (4%) of patients who had history of MI in past and around 45 (85%) had Triple Vessel Disease (TVD). Conclusion: Among all the pre-operative risk factors HTN and H/O MI had a significant association in improvement in LVEF, similarly thyroid status had a strong association with improvement in NYHA
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Yadav et al. (2022) conducted a cross-sectional in Coronary Artery Disease undergoing CABG (n=54). Preoperative risk factors (Hypertension, History of MI, Thyroid status) vs. Absence of respective risk factors was evaluated on Change in Left Ventricular Ejection Fraction (LVEF) and NYHA class at 3 months follow-up (p=0.002). Preoperative hypertension (p=0.002) and history of myocardial infarction (p=0.004) were significantly associated with postoperative changes in LVEF, while abnormal thyroid status was strongly associated with improvement in NYHA class (p=0.006).
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