Key result
Fluorouracil-based chemotherapy can trigger severe coronary vasospasm mimicking acute myocardial infarction.
Highlights a case of suspected drug-associated coronary vasospasm with transient ST-segment elevation during multi-agent chemotherapy containing fluorouracil in a patient with gastric cancer.
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Clinicians should monitor for vasospasm during fluorouracil chemotherapy; this single case leaves open definitive causality in multi-agent regimens.
Fluorouracil (5-FU) can induce coronary vasospasm that mimics ST-segment elevation myocardial infarction. During multi-agent chemotherapy, attribution...
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Mohseni et al. (2026) studied this question. Fluorouracil-containing multi-agent chemotherapy induced suspected coronary vasospasm with transient ST-segment elevation mimicking myocardial infarction in a patient with gastric cancer.
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