Supplementary figure highlights aberrant circRNA expression and NLRP3 activation in esophageal squamous cell carcinoma, suggesting new pathways for therapy.
Key Points
Main finding indicates 393 differentially expressed circRNAs in esophageal squamous cell carcinoma compared to normal tissues.
Key evidence shows 158 circRNAs were upregulated and 235 downregulated, significantly affecting disease progression.
Approach utilized violin plots, volcano plots, and heat maps to visualize circRNA expression in tumor and normal tissues.
Significance lies in uncovering the role of circRNA and NLRP3 activation, potentially guiding new treatment strategies.