Supplementary Figure S1 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Ya-Yun Cheng; Beth L. Worley; Zaineb Javed; Amal T. Elhaw; Priscilla W. Tang; Sarah Al-Saad; Shriya Kamlapurkar; Sierra R. White; Apoorva Uboveja; Karthikeyan Mythreye; Katherine M. Aird; Traci A. Czyzyk; Nadine Hempel

doi:10.1158/2767-9764.29607303

July 21, 2025

Supplementary Figure S1 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

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Key Points

MAIN FINDING: Loss of the cell adhesion molecule MPZL3 is linked to increased epithelial-mesenchymal transition (EMT) in ovarian cancer.
KEY EVIDENCE: Analysis of the TCGA ovarian adenocarcinoma dataset shows a correlation between MPZL3 and overall survival rates.
APPROACH: The study used genomic data to assess cell adhesion molecule (CNA) impacts on patient outcomes.
SIGNIFICANCE: Understanding MPZL3's role enhances insights into ovarian cancer progression and potential therapeutic targets.

Implication

Supplementary data reveals how loss of cell adhesion molecule MPZL3 affects overall survival in ovarian cancer patients, indicating its role in disease progression.

Abstract

Supplementary Figure S1. Percentage of MPZL3 CNA and CNA based overall survival in TCGA ovarian adenocarcinoma dataset.

Discussion

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Cite This Study

Cheng et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd1e6 https://doi.org/10.1158/2767-9764.29607303

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Supplementary Figure S1 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S1 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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