Supplementary Figure S2 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Ya-Yun Cheng; Beth L. Worley; Zaineb Javed; Amal T. Elhaw; Priscilla W. Tang; Sarah Al-Saad; Shriya Kamlapurkar; Sierra R. White; Apoorva Uboveja; Karthikeyan Mythreye; Katherine M. Aird; Traci A. Czyzyk; Nadine Hempel

doi:10.1158/2767-9764.29607300

July 21, 2025

Supplementary Figure S2 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

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Key Points

MAIN FINDING: MPZL3 knock-down promotes epithelial-mesenchymal transition (EMT) in ovarian cancer cells.
KEY EVIDENCE: Analysis shows altered transcription of key genes related to EMT and cell cycle after MPZL3 knock-down.
APPROACH: The study utilized gene expression analysis on ovarian cancer cells post MPZL3 knock-down.
SIGNIFICANCE: Understanding the role of MPZL3 in EMT may highlight new therapeutic targets for ovarian cancer treatment.

Implication

Experiments reveal MPZL3 knock-down alters transcription of EMT and cell cycle-related genes in ovarian cancer cells, suggesting significant impacts on tumor behavior.

Abstract

Supplementary Figure S2. MPZL3 knock-down affects transcription of EMT and cell cycle-related genes in ovarian cancer cells.

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Cite This Study

Cheng et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd1ec https://doi.org/10.1158/2767-9764.29607300

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Supplementary Figure S2 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S2 from Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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