August 2, 2025

Table S10 from RGN6024 Is a Brain-Penetrant, Small-Molecule Tubulin Destabilizer for the Treatment of Glioblastoma

View Full Paper

Ask AI

Bookmark

MAIN FINDING: RGN6024 is identified as a brain-penetrant tubulin destabilizer suitable for glioblastoma therapy.
KEY EVIDENCE: Administration of RGN6024 at 30 mg/kg resulted in measurable plasma and brain levels in ICR mice.
APPROACH: The study utilized oral dosing in ICR mice to assess the pharmacokinetics of RGN6024.
SIGNIFICANCE: These findings support the development of RGN6024 as a promising treatment option for glioblastoma.

No abstract yet

We only have this paper's title and publication details.

Research shows RGN6024 penetrates the brain effectively in ICR mice, suggesting its potential as a glioblastoma treatment.

Plasma and brain levels of RGN6024 after a 30 mg/kg oral dose in ICR mice

No takes yet. Share an insight, caveat, or question.

Patrón et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Research shows RGN6024 penetrates the brain effectively in ICR mice, suggesting its potential as a glioblastoma treatment.

Plasma and brain levels of RGN6024 after a 30 mg/kg oral dose in ICR mice