Supplementary Figure S27 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

MAIN FINDING: Single-cell eQTL mapping reveals genetic control linked to malignant transformation in colorectal cancer.
KEY EVIDENCE: Functional annotation of the rs4794979 region supports subtype-specific genetic mechanisms.
APPROACH: The study utilizes single-cell RNA sequencing to identify eQTLs and their implications in cancer.
SIGNIFICANCE: Understanding genetic control aids in developing targeted therapies for colorectal cancer subtypes.

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Single-cell eQTL mapping uncovers genetic control in malignant transformation of colorectal cancer, highlighting subtype-specific mechanisms.

Supplementary Figure 27 shows functional annotation for rs4794979 region.

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Chen et al. (2025) studied this question.

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