Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30028688

Key Points

Dietary fiber shows varied effects on immune checkpoint blockade efficacy across different murine tumor models.
The analysis of serum metabolite peak areas reveals no consistent trend linked to dietary fiber intake.
This study employed a comprehensive observational approach across multiple murine tumor models.
The findings highlight the complexity of dietary interventions in cancer treatment, calling for further research.

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Implication

Observational analysis shows inconsistent effects of dietary fiber on immune checkpoint blockade efficacy in murine tumor models, suggesting potential variability.

Abstract

Serum metabolite peak areas from the PyMT model

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd0295f https://doi.org/10.1158/0008-5472.30028688

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Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S7 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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